Mexico City is one of the largest cities, not just in Latin America, but also one of the most expansive cities of the world, and choosing the right neighborhood to stay can shape your travel experience here.
Over the years, we have visited Mexico City on various occasions and have stayed in different areas.
So, based on our experience, we shortlist 6 best areas to stay in Mexico City. Each area has its own highlights in terms of activities, places of interests, nightlife, restaurants and transportation.
To help you decide where to stay in Mexico City, in this blog post, we go through the details of each area and share our top picks for Mexico City hotels in each neighborhood.

Best Areas and Our Top Hotel Picks: Quick View
Here is our take from staying in different areas of Mexico City over the years:
| Areas | Why? | Hotel Picks |
|---|---|---|
| Centro Historico / Zocalo | For first timers, history, museums | Gran Hotel Ciudad de Mexico |
| Polanco | For upscale luxury hotels and restaurants | Pug Seal Polanco Allan Poe |
| Roma | For nightlife, art-deco architecture, trendy atmosphere | Colima 71 – Casa de Arte Hotel |
| Condesa | For nightlife, trendy cafes, galleries | Casa Mali by Dominion Hotel |
| Coyoacan & San Angel | For artistic and Bohemian vibes, home of Frida Kahlo | H21 Hospedaje Boutique |
Best Areas to Stay in Mexico City: What to Know
Before getting into the details of each of these, let’s first address some questions you may have about the best areas to stay in Mexico City.
What is the best area to stay in Mexico City for first timers?
We recommend staying closer to the Historic Center in Mexico City for better access to the Mexico City attractions in Zocalo, Polanco, Roma or Condesa.
On our first visit, we chose the Roma neighborhood and found it perfect for exploring the city as first-timers.
Which areas of Mexico City are safe for tourists?
We find areas such as Polanco, Condesa, Roma and Coyoacán to be relatively safe, even fine for evening strolls after dark.
But like any big city anywhere in the world, it is important to stay cautious and follow your instincts and use common sense.
What is our favorite area to stay in Mexico City?
There are so many neighborhoods in Mexico City, each with a different atmosphere. Over time we found Coyoacan to be our favorite area for its artsy and bohemian vibes.
➡️ Related Reading: 4 Days in Mexico City Itinerary.
Centro Histórico: The Heart of History
The Historic Center of Mexico City, a UNESCO World Heritage site, offers historical sites and opportunities for cultural immersion. Even after our multiple visits, we find something new to explore in the heart of Mexico City.
Just stepping out of your hotel in Zocalo, you can access historic buildings in Mexico City’s main square, explore nearby art galleries and museums, try various restaurants and street food, and shop at modern retail stores housed in century-old buildings.
Why should you stay in Centro Historico?
✅ Walkable from historical landmarks and museums
✅ Close to traditional Mexican restaurants and street food
✅ For short term visits, easier to explore the landmarks and convenient access to other parts of the city
What to keep in mind about staying in Centro Histórico
🏛️ As it houses so many landmarks, the area is busy and bustling
🧳 Some parts of the Centro Historico can feel touristy and commercialized at times
Our Top Activities in Centro Historico of Mexico City
✅ Take a self-guided walk around Zócalo Square and the surrounding streets, exploring sites like the Templo Mayor, Palacio de Bellas Artes, and the many art, culture, and history museums nearby.
✅ For a deeper experience, join a guided walking tour of Centro Histórico. This is our preferred way to start understanding a city and it sets the tone for discovering more about the City’s history and culture.
✅ Mexican mural art has a fascinating history, with masterpieces by Diego Rivera adorning places like the National Palace and the Ministry of Education building, among others around the Zócalo area. Discovering these murals was an incredible experience for us. The best way to fully appreciate Mexico City’s muralism is to join a guided tour, which includes entrance tickets to key museums.

Top Hotel Picks in Centro Histórico
Gran Hotel Ciudad de México
Why Stay: Choose Gran Hotel Ciudad de Mexico for its unique blend of history and grandeur.
From the moment you enter, the stunning stained-glass ceiling, designed by the renowned Jacques Grüber, invites you into a space filled with timeless Art Nouveau elegance.
🏨 Its unparalleled location on Zócalo Square, with rooms overlooking the plaza, places you right in the center of Mexico City’s cultural and historical heritage.
✨ The rooftop terrace offers breathtaking views of the Zócalo and surrounding landmarks, whether you are enjoying your morning coffee or relaxing with an evening cocktail.
Book your stay at Gran Hotel Ciudad de Mexico here ⬇️
Book on Booking.com → Book on Expedia →
Hotel Zócalo Central & Rooftop Mexico City
Why Stay: If you are drawn to a mix of colonial architecture and contemporary luxury, this hotel is the perfect choice.
🏨 Ideally located just steps from the Zócalo, Hotel Zocalo Central & Rooftop offers rooms with spectacular views of the square. Each room features charming antique-style wooden furniture alongside modern desks and amenities, creating a cozy yet sophisticated ambiance.
✨ The rooftop restaurant delights with traditional Mexican flavors and offers panoramic views of the Zócalo.
Book your stay at Hotel Zocalo Central & Rooftop here ⬇️
Book on Booking.com → Book on Expedia →Hotel Catedral
Why Stay: This hotel is known for its warm hospitality and close proximity to the Metropolitan Cathedral.
🏨 The rooms, ranging from Junior suites to King and Superior suites with terraces, feature simple, well-maintained, modern decor and amenities at a moderate price for this prime location.
✨ With easy access to major attractions and nearby highlights, Hotel Catedral is an excellent choice for travelers looking to make the most of their time in the city.
Book your stay at Hotel Catedral here ⬇️
Book on Booking.com → Book on Expedia →Hotel Principal
Why Stay: With a history spanning nearly a century, Hotel Principal offers an affordable stay in a thoughtfully preserved setting that feels like stepping back in time.
🏨 Accommodations range from simple standard rooms to larger family accommodations, all at budget-friendly rates. Its central location makes it an especially appealing option for visitors.
✨ Enjoy breakfast on the terrace, where you are treated to open views of the surroundings.
Book your stay at Hotel Principal here ⬇️
Book on Booking.com → Book on Expedia →Barrio Downtown Mexico City Hostel
Why Stay: Perfect for backpackers and creatives, this boutique hostel is a lively, budget-friendly choice offering both private rooms and dorms near Centro Histórico.
🏨 The eclectic decor, colorful murals capturing the spirit of Mexico City, and a lively social atmosphere make Barrio Downtown Mexico City Hostel an ideal pick for those seeking both style and community.
✨ The rooftop pool provides a unique, relaxed setting, all within walking distance of the main attractions in Centro Histórico.
Book your stay at Barrio Downtown Mexico City Hostel here ⬇️
Book on Booking.com → Book on Expedia →Polanco: Elegance Meets Culture
We found Polanco to be a unique contrast to the historic allure of Centro Histórico, presenting travelers with an upscale, cosmopolitan experience.
Polanco is an affluent neighborhood with cosmopolitan vibes. Think wide, leafy boulevards lined with luxury boutiques, some of Mexico City’s best restaurants and galleries featuring world-class art.
Whether you are splurging on boutique accommodations or choosing a sleek apartment rental that feels like home, staying in Polanco lets you experience the contemporary and plush side of Mexico City.
Why should you stay in Polanco?
✅ Walkable and comparatively safe neighborhood
✅ A gastronomy hub with some of the best restaurants of Mexico City
✅ Easy access to Centro Historico and other attractions
✅ High-end shopping area with boutique and popular brands
What to keep in mind about staying in Polanco
💰 Polanco’s charm comes at a price. It is one of Mexico City’s most expensive neighborhoods.
🌃 Polanco tends to be quieter in the evenings compared to the energetic nightlife scenes of Roma or Condesa. Here, nighttime experiences are more refined and sophisticated, perfect for those seeking a more relaxed atmosphere.
Our Top Activities in Polanco, Mexico City
✅ Walk around the Polanco neighborhood, a different experience than the Centro Historico.
✅ Explore the museums near Polanco, such as the Soumya Museum and the Anthropology Museum in Chapultepec Park.
✅ Eat at some of the top restaurants of Mexico City, serving Mexican and world cuisines. If you want to discover what to expect, go for this food tour that that includes tasting cuisines from different states of Mexico.

Top Hotel Picks in Polanco
Pug Seal Polanco Allan Poe
Why Stay: Pug Seal Polanco Allan Poe is a boutique hotel set in a mansion, offering chic hospitality with a quirky edge.
🏨 The rooms and suites exude personality and warmth, making it comfortable and inviting. We like their artistic designs that blend traditional Mexican elements, bold colors, unique touches and modern flair, making your stay both comfortable and visually inspiring.
✨ Enjoy excellent breakfasts and take advantage of complimentary bikes, memorable touches that enhance your experience.
Book your stay at Pug Seal Polanco Allan Poe here ⬇️
Book on Booking.com → Book on Expedia →
Casa Polanco Hotel Boutique
Why Stay: Casa Polanco is a stunning boutique hotel housed in a beautifully restored 1940s residence, seamlessly blending heritage with modern luxury.
🏨 The premium suites feature stylish interiors, excellent decor, and a wealth of modern in-room amenities, ensuring a comfortable and elegant stay.
✨ After a day of exploring, unwind in the inviting lounge and terrace areas. The hotel also boasts gym facilities, an in-house restaurant serving Mexican delicacies, and a bar for relaxing evenings.
Book your stay at Casa Polanco Hotel Boutique here ⬇️
Book on Booking.com → Book on Expedia →Presidente InterContinental Mexico City by IHG
Why Stay: This iconic hotel is all about reliable luxury and convenience, offering sweeping views of both Chapultepec Park and the city skyline.
🏨 With a wide range of accommodation options and amenities, Presidente InterContinental is perfect for couples, families, or business travelers. Multiple on-site dining venues let you savor global flavors without needing to leave the hotel.
✨ Chapultepec Park is just a short walk away, making it easy to explore one of Mexico City’s most famous green spaces.
Book your stay at Presidente InterContinental here ⬇️
Book on Booking.com → Book on Expedia →Ana Polanco Apartments
Why Stay: For those seeking a home-away-from-home atmosphere, Ana Polanco Apartments are an excellent choice, blending hotel-style luxury with apartment living in the heart of Polanco.
🏨 These stylish, spacious apartments offer full kitchens, modern decor, and exceptional privacy, perfect for both short-term and extended stays.
✨ With a central location, you will be able to explore Polanco like a local while enjoying the comfort and convenience of hotel-level amenities.
Book your stay at Ana Polanco Apartments here ⬇️
Book on Booking.com → Book on Expedia →Coyoacan & San Angel: Artsy Bohemian Vibe
Coyoacan and San Angel areas are located little further, in the southern part of the Mexico City.
Birthplace of Frida Kahlo, Coyoacan is a bohemian neighborhood with cobblestone streets and centuries-old architectures.
Strolling through the quiet streets, hanging out at lively plazas, exploring the Coyoacan market and inviting cafes, Coyoacan turned into our favorite part of Mexico City.
The atmosphere here is artistic and laid-back, offering a refreshing contrast to the high-energy vibe of the central neighborhoods.
San Angel adjacent to Coyoacan, is smaller but just as captivating. We enjoyed wandering around Plaza San Jacinto, where painters and artists display their work outdoors. The Bazar Sabado in San Angel also features indoor shops showcasing creations by talented local artisans.
➡️ Related Reading: Our experience of visiting the Frida Kahlo Museum
Why should you stay in Coyoacan?
✅ Walkable, with cobblestone streets
✅ Multiple green plazas to unwind
✅ One of the safer neighborhoods of the city
✅ Home to Frida Kahlo Museum, close to UNAM
✅ Comparatively closer to the attractions in the southern areas of the city, like Xochimilco
✅ Interesting local artisan markets in Coyoacan and San Angel
What to Keep in Mind about staying in Coyoacan
💰 Coyoacan is a bit further from the Centro Historico and the central districts of Mexico City
Our Top Activities in Coyoacan and San Angel, Mexico City
✅ Explore the Coyoacan and San Angel neighborhoods, plazas. Check out the San Angel’s ‘Bazar Sabado’ or Saturday Market and visit the Coyoacan Market.
✅ We find the story of Frida Kahlo inspiring. Visiting ‘Casa Azul’, or the Frida Kahlo museum elevated our feelings. You can take this guided tour about her life and works at the museum that includes the entrance tickets.
✅ We also recommend the El Carmen Museum in San Angel, known for housing the mummies of San Angel and its fascinating history.
✅ For a different perspective, visit the UNESCO World Heritage-listed UNAM campus (Universidad Nacional Autónoma de México) to admire its unique architecture, impressive murals, and lush green spaces.

Top Hotel Picks in Coyoacan
H21 Hospedaje Boutique
Why Stay: This boutique gem merges modern style with intimate hospitality located centrally in Coyoacan.
🏨 Inspired by the artistic legacy of the neighborhood, each room is uniquely designed with thoughtful details to match its surroundings. Known for its personalized attention, H21 Hospedaje Boutique is perfect for travelers looking for exceptional service, making it comfortable and inviting.
✨ It is located mere steps from the Frida Kahlo Museum, allowing easy access to one of Coyoacán’s biggest attractions.
Book your stay at H21 Hospedaje Boutique here ⬇️
Book on Booking.com → Book on Expedia →
Agata Hotel Boutique & Spa
Why Stay: Agata Hotel Boutique & Spa rightly mixes boutique lodging with wellness though their spa services and high-end design.
🏨 The room decors complement the theme of wellness, relaxation and comfort. The interesting lamp designs in the rooms and bathrooms add to the ambience of the accommodation.
✨ After exploring Coyoacán, unwind with a massage or treatment in their serene spa facilities or the sun terrace.
Book your stay at Agata Hotel Boutique & Spa here ⬇️
Book on Booking.com → Book on Expedia →Casa Tuna
Why Stay: For travelers seeking a cozy, boutique experience in the heart of Coyoacán, Casa Tuna offers a tranquil retreat with a Mexican charm.
🏨 The suites and rooms have soothing color themes, with contemporary furniture, modern interiors and bathroom amenities. It is perfect for travelers wanting a quiet and authentic stay near cultural landmarks of Coyoacan.
✨ The hotel has multiple interesting places to hangout – courtyard, sun terrace and a garden area. Also, the kitchenette works perfect to have your quick bites prepared during the stay.
Book your stay at Casa Tuna here ⬇️
Book on Booking.com → Book on Expedia →Suites Perisur Apartamentos Amueblados
Why Stay: For travelers wanting elevated, spacious accommodations, Suites Perisur stands out with modern apartments and amenities.
🏨 The suites are spacious with sitting spaces and amenities like coffee maker in the room. Though technically closer to the southern edge of Coyoacán, it’s an excellent option for longer stays or families needing larger spaces.
✨ The lounge terrace has amazing views of the city. There is a small but well-equipped gym as part of the facilities.
Book your stay at Suites Perisur Apartamentos here ⬇️
Book on Booking.com → Book on Expedia →Hostal Cuija Coyoacan Berlin 268
Why Stay: Best suited for budget travelers and backpackers, this charming hostel provides a laid-back atmosphere at affordable prices in an excellent location.
🏨 The accommodation at Hostal Cuija Coyoacan Berlin 268 offers basic amenities at affordable rates for shared dormitories or private rooms with garden views.
✨ It is in an exceptional location near Coyoacán’s plazas and markets and offers the perfect base for exploring the area on foot. You can relax at their sun terrace or garden after your day’s exploration.
Book your stay at Hostal Cuija Coyoacan Berlin 268 here ⬇️
Book on Booking.com → Book on Expedia →Roma & Condesa: Trendy and Vibrant
Condesa is a trendy neighborhood known for its art-deco architecture and vibrant nightlife, while neighboring Roma charms both locals and visitors alike.
Roma and Condesa offer a perfect blend of bohemian spirit and modern cool. Wander through streets lined with indie boutiques and discover excellent eateries catering to foodies, coffee enthusiasts and nightlife lovers.
Why should you stay in Roma & Condesa?
✅ Incredibly walkable, and interesting streets like Avenida Alvaro Obregon, Colima Street, and Paseo de la Reforma connecting Chapultepec Park with the historic center.
✅ Easy access to top-notch eateries, bars and boutiques
✅ Explore art galleries during the day, and experience the nightlife at the end of the day
What to keep in mind about staying in Roma & Condesa?
👣 These areas are popular with locals and tourists, meaning streets and attractions can get crowded, especially during weekends and evenings.
Our Top Activities in Roma & Condesa, Mexico City
✅ Stroll the tree-lined avenues of Roma and Condesa, such as Avenida Alvaro Obregon, where you will find inviting cafes, galleries, and striking art-deco architecture. These neighborhoods are perfect for enjoying street life and people-watching.
✅ Explore the local museums, the expansive Chapultepec Park, and the many plazas and public parks scattered throughout Condesa and Roma.
✅ Do not miss the renowned culinary scene – these areas are a haven for food lovers. We recommend this food and beverage tasting tour with tacos, mezcal, and cocktails on the list.

Top Hotel Picks in Roma & Condesa
Colima 71 – Casa de Arte Hotel
Why Stay: This boutique hotel offers a blend of modern style and intimate hospitality, ideally situated in the heart of Roma Norte.
🏨 Inspired by its artful surroundings, Colima 71 – Casa de Arte Hotel features thoughtfully curated interiors, blending contemporary design with classic artistic touches. Each room has a unique decor and come with a kitchenette.
✨ Centrally located, you are within walking distance of trendy cafes, galleries, and the bustling scenes of one of Mexico City’s most vibrant neighborhoods.
Book your stay at Colima 71 – Casa de Arte Hotel here ⬇️
Book on Booking.com → Book on Expedia →NaNa Vida CDMX
Why Stay: This boutique retreat expertly blends comfort, culture and charm, ideal for those seeking authenticity in the heart of Mexico City.
🏨 Known for its warm, personalized service and beautifully designed spaces, NaNa Visa CDMX celebrates Mexican craftsmanship. The decor immerses guests in the country’s rich heritage while offering all the modern luxuries you expect.
✨ The sun terrace has stunning views of the city. Located in Roma Norte, it offers easy access to cultural landmarks, premier dining spots, and art venues.
Book your stay at NaNa Visa CDMX here ⬇️
Book on Booking.com → Book on Expedia →
Four Points by Sheraton Mexico City Colonia Roma
Why Stay: A premium option from a well-known brand for travelers seeking quality and convenience in Roma Norte.
🏨 With modern, spacious rooms and dependable amenities, Four Points by Sheraton Mexico City Colonia Roma caters to business and leisure travelers alike. A rooftop terrace and onsite restaurant ensure comfort and indulgence during your stay.
✨ Centrally located in Roma Norte, you will be just steps from iconic restaurants, lively nightlife and the area’s celebrated architecture.
Book your stay at Four Points by Sheraton Mexico City Colonia Roma here ⬇️
Book on Booking.com → Book on Expedia →Casa Malí by Dominion Boutique Hotel
Why Stay: A luxurious extended-stay boutique option with housekeeping service for those seeking style and comfort in the Condesa neighborhood.
🏨 Every suite is pleasingly designed and features full kitchenettes, making Casa Malí by Dominion Boutique Hotel an ideal choice for longer visits. The rooftop terrace, with views of greenery, adds an extra layer of indulgence.
✨ Overlooking Parque México, this hotel provides a serene yet central base for exploring Condesa and beyond. You will enjoy the greenery, as well as, the area’s renowned cafes and restaurants.
Book your stay at Casa Malí by Dominion Boutique Hotel here ⬇️
Book on Booking.com → Book on Expedia →La Palomilla Bed & Breakfast
Why Stay: A cozy, eco-friendly bed and breakfast offering a personal touch, making you feel at home in Mexico City.
🏨 This charming accommodation provides comfortable, stylish rooms filled with unique details and Mexican artwork. Its intimate atmosphere and vibrant colors create an authentic connection to Mexican culture.
✨ Conveniently located in Roma, from La Palomilla Bed & Breakfast, you can have easy access to parks, cafes, and cultural hotspots in one of the city’s trendiest location.
Book your stay at La Palomilla Bed & Breakfast here ⬇️
Book on Booking.com → Book on Expedia →Hotel Casa Cuenca
Why Stay: A quaint hotel offering warm hospitality and a relaxing ambiance in a picturesque setting.
🏨 Featuring thoughtfully designed interiors, Hotel Casa Cuenca combines traditional Mexican aesthetics with contemporary touches and interesting light designs. The spacious rooms feature comfortable sitting areas with sofas.
✨ Located in the heart of Condesa, you are surrounded by tree-lined streets, eateries and lush parks while staying close to cultural landmarks.
Book your stay at Hotel Casa Cuenca here ⬇️
Book on Booking.com → Book on Expedia →Plan Your Mexico City Trip
Travel Resources
- Flights: Skyscanner
- Hotels: Booking.com | Expedia
- Tours: Viator | GetYourGuide
- Travel Insurance:
- Heymondo (get 5% off)
- SafetyWing Nomad Insurance
- eSIMs:
- Transfers: Bookaway. Code PARADISE5 for 5% off
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